一株神舟十号飞船分离少动鞘氨醇单胞菌基因组测序结果及分析

摘要

A strain of bacterium, LCT⁃SP1, was isolated from Shenzhou⁃10 spacecraft, and identi⁃fied as Sphingomonas paucimobilis by 16S rDNA sequencing. Its genomic sequence was obtained by the Illumina sequencing platform. After the annotation, 3884 protein⁃coding genes, 3 rRNA genes and 47 tRNA genes were found. Based on the COG and GO analysis, the gene⁃information of the bacteria was obtained. A phylogenetic tree of this bacterium was constructed. The genome analysis shows that the bacterium has corrosion⁃related genes that might promote its adaptation to the harsh environment. 574 virulence associated genes and 57 antibiotic⁃resistant genes were also found in the genome, which indicated the potential pathogenicity of the bacterium.%在神舟十号飞船中检测出一株下行菌，16 S rDNA鉴定后命名为少动鞘氨醇单胞菌LCT⁃SP1。通过对该菌基因组进行二代测序及基因注释，发现该菌包含3884个蛋白编码基因、3个rRNA编码基因和47个tRNA编码基因。通过对该菌基因组进行COG、GO分析及注释，完善了该菌的遗传信息，并建立了该菌的系统发育树。分析发现该菌包含腐蚀相关基因并可适应恶劣的生存环境。通过基因注释发现该菌包含574个毒力相关基因以及57个耐药相关基因，提示该菌存在潜在的致病性。