开放性椎体成形术治疗脊柱转移瘤和多发性骨髓瘤效果分析

摘要

Objective To analysis and explore the clinical effect of open vertebroplasty for the treatment of spinal metastases and multiple myeloma .Methods From February 2010 to February 2012 ,the implementation of open vertebroplasty on 12 cases of spinal metastases and 10 cases of multiple myeloma in the hospital .Compared with preoperative pain scores and postoperative pain score ,and the activities of patients before and after operation were an-alyzed and discussed .Results Pain within 3 days after operation in patients with better ease ,preoperative pain score was (7 .0 ± 1 .0)points ,postoperative pain score was (1 .5 ± 0 .5)points ,P<0 .05 .Activities of patients with postop-erative had also been greatly improved ,1 years of follow-up of the patients ,10 cases died of primary disease in 22 ca-ses ,the other 12 patients had stable disease .Conclusion For the patients with spinal metastases or multiple myelo-ma ,take open vertebroplasty can improve the patient's activities ,alleviate the pain ,it is worth being popularized in clinical .%目的分析与探讨开放性椎体成形术对于脊柱转移瘤与多发性骨髓瘤的临床效果。方法选取重庆市奉节县人民医院2010年2月至2012年2月收治的脊柱转移瘤患者共12例，多发性骨髓瘤患者共10例，对其实施开放性椎体成形术。对比患者术前疼痛评分与术后疼痛评分，并对患者的手术前后活动能力进行分析与探讨。结果所有患者在接受手术后3d内疼痛情况均得到良好缓解，术前疼痛评分为（7．0±1．0）分，术后疼痛评分为（1．5±0．5）分，差异有统计学意义（P＜0．05）。患者术后活动能力也得到了较大的改善，对患者进行为期1年的随访，22例患者中共10例死于原发病，其余12例患者病情稳定。结论对于脊柱转移瘤与多发性骨髓瘤患者，采取开放性椎体成形术能够改善患者的活动能力，缓解其疼痛，因此在临床上值得推广应用。