首页> 中文期刊> 《检验医学与临床》 >汉佩尔辨识法在酶联免疫吸附试验室内质控中的应用

汉佩尔辨识法在酶联免疫吸附试验室内质控中的应用

         

摘要

目的 探讨汉佩尔辨识法(Hampel identifier)在室内质控图中的应用 ,评估其对质控离群值的检出能力.方法 使用弱阳性HIV质控品和常规标本一起检测 ,连续测定20次 ,收集原始数据 ,并在其基础上衍生模拟数据 ;然后对原始数据和模拟数据进行分析并绘制Z-分数图、Hampel identifier (Zi-分数图)与箱式图 ,比较3种质控图对离群值的检出能力.结果 对于非正态数据 ,Hampel identifier与箱式图的离群值检出能力一致 ,均高于Zi-分数图.结论 使用多种离群值检测方法的功能、应用条件及其限制 ,防止离群值的漏判.%Objective To study the value of Hampel identifier in internal quality control and to assess the de-tection ability of quality control outliers .Methods The weak positive quality product of HIV together with routine specimens were detected for 20 times ,raw data and simulation data derived on the basis of the raw data were collect-ed and analyzed ,Z-scores figure ,Hampel identifier (Zi-scores figure) ,box plot correspondingly were drawed ,and the ability of outlier detection about the three kinds of quality control charts were compared .Results Hampel identifier was consistent with the box plot on outlier detection ability for abnormal distribution data ,both were superior to Z-score chart .Conclusion Medical laboratory managers should master functions ,application conditions and limitations of outlier detection methods to prevent the missing outliers .

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