中药浴联合西医治疗慢性肾小球肾炎慢性肾衰竭的疗效观察

摘要

Objective To investigate the effects of Chinese herbs medicated bath combined with Western medi‐cine in treatment of chronic renal failure caused by chronic glomerulonephritis .Methods A total of 100 patients with chronic renal failure (compensatory period) caused by hypertensive renal damage from December 2012 to December 2013 were recruited in this study and divided into treatment group and control group ,50 patients in each group .Pa‐tients in the control group were given routine Western medicine for treatment while patients in the treatment group were treated with Chinese herbs medicated bath combined with Western medicine ,urine protein quantity (PRO) ,ser‐um Creatinine (SCr) ,blood urea nitrogen (BUN) of 24 hours were monitored ,and the clinical efficacy were evalua‐ted .Results The curative effective rate of the treatment group after treatment was 86 .00% ,which was significant higher than 66 .00% of the control group ,the difference was statisticaly significant (P<0 .05) .PRO ,SCr ,BUN in two groups after treatment were better than those before treatment (P<0 .05) ,and those in the treatment group was significantly better than those in the control group (P<0 .05) .The recurrence rates in the 1st ,6th month after treat‐ment in the treatment group were 4 .0% ,8 .0% respectively ,which were significantly better than 20 .0% ,36 .0% of the control group ,with statistical significant difference (P< 0 .05) .Conclusion The Chinese herbs medicated bath combined with Western medicine has an obvious clinical curative effect in the treatment of chronic renal failure caused by chronic glomerulonephritis .It could effectively relieve the clinical symptoms of patients and reduce the recurrence rate ,which is worthy of being generalized in clinic .%目的：探讨中药浴联合西医治疗慢性肾小球肾炎慢性肾衰竭临床疗效。方法收集2012年12月至2013年12月接受治疗的慢性肾小球肾炎慢性肾衰竭（衰竭期）患者100例，随机分为治疗组与对照组各50例，对照组给予西医常规治疗；治疗组给予中药浴联合西医治疗，监测患者24 h尿蛋白定量（PRO）、血肌酐（SCr）、血尿素氮（BU N ），评价临床疗效。结果治疗组患者临床有效率为86．00％，高于对照组的66．00％，差异有统计学意义（P＜0．05）。两组患者治疗后PRO、SCr、BUN均优于治疗前，且治疗组患者明显优于对照组，差异均有统计学意义（P＜0．05）。治疗组患者第1、6个月的复发率为4．0％、8．0％，明显低于对照组的20．0％、36．0％，差异有统计学意义（P＜0．05）。结论中药浴联合西医治疗慢性肾小球肾炎慢性肾衰竭的临床疗效确切，可有效改善患者临床症状，降低复发率，值得临床推广。