EB病毒和支原体双重感染传染性单核细胞增多症的临床特征

摘要

目的 探讨EB病毒(EBV)和支原体(MP)双重感染传染性单核细胞增多症(IM)的临床特征.方法 总结22例由EBV和M P双重感染导致IM的临床表现,将其与单独EBV感染导致的IM进行比较.结果 2组间临床表现比较:双重感染组的高热持续时间明显长于EB V感染组,双重感染组的肺炎发生率和咽峡炎发生率均明显高于EB V感染组,差异均有统计学意义(P<0.05).2组间实验室指标比较,双重感染组肝功能异常的发生率明显高于EBV感染组,差异有统计学意义(P<0.05).结论 EBV和M P双重感染IM临床症状较重,发热持续时间较长,住院时间较长,并发症如血小板减少症、肺炎和贫血的发生率较高.%Objective To explore the characteristics of infectious mononucleosis with dual infection of Epstein-Barr virus and mycoplasma .Methods The characteristics of 22 children with IM infected by EBV/MP were retrospectively analyzed and compared with the EBV infection cases .Results Clinical manifestations :the duration of fever was significantly higher in the EBV/MP dual infection group than that in the EBV infection group ,the incidence of pneumonia and angina were significantly higher in the dual in-fection group than that in the EBV infection group ,the differences were statistically significant (P<0 .05) .Laboratory findings ,the rate of atypical lymphocyte and the incidence of abnormal liver function were significantly higher in the dual infection group than that in the EBV infection group ,the difference was statistically significant (P<0 .05) .Conclusion The IM cases with EBV/MP onger febrile period and a higher incidence of complications ,including thrombocytopenia ,pneumonia and anemia ,compared with sin-gle EBV infection .