病毒性肝炎患者血清sICAM-1、IL-6及TNF-α水平检测分析

摘要

应用酶联免疫吸附法检测了43名对照组和129例各类病毒性肝炎患者血清sICAM-1、IL-6及TNF-α水平含量.结果表明:急、慢性肝炎及肝硬化患者血清sICAM-1水平明显高于对照组(P＜0.01),慢性重型肝炎组明显高于中度和轻度慢性肝炎组(P＜0.01),各类肝炎患者血清sICAM-1水平与ALT、TBi1均呈明显正相关;各类肝炎及肝硬化患者血清IL-6和TNF-α水平也较对照组显著升高(P＜0.01).提示:病毒性肝炎患者血清sICAM-1、IL-6和TNF-α水平均明显增高,其水平的高低在一定程度上反映了机体免疫功能状态、肝损害及炎症程度.