参麦注射液对慢性收缩性心力衰竭患者心功能及BNP的影响

摘要

[目的]观察参麦注射液对慢性收缩性心力衰竭患者心功能及B型尿钠肽(BNP)的影响.[方法]将2008年6月至2010年10月间我院收治的120例慢性收缩期心力衰竭患者随机分为治疗组和对照组各60例.对照组给予吸氧、洋地黄、利尿剂、血管紧张素转换酶抑制剂、硝酸酯制荆治疗.治疗组在对照组基础上静脉滴注参麦注射液50mL/d,连续14d为1个疗程.观察两组治疗前后心功能,左室射血分数及血象BNP变化.[结果]治疗组总有效率明显高于对照组,两组比较差异有统计学意义(P＜0.05).治疗组左室射血分数升高及血荣BNP下降较对照组更明显(P＜0.05).[结论]参麦注射液可改善慢性收缩性心力衰竭患者心功能,提高左室射血分数,降低血浆BNP水平.%[Objective] To observe the influence of Shenmai injection on contractive heart failure patients' heart function and BNP. [Method] RandomLy divide 120 cases into treatment and control groups with 60 in each one; the control group takes oxygen, foreign rehmannia, diuretics, ACE inhibitor and nitric ether preparation; the treatment one added with intravenous drip of Shenmai injection; observe both groups' heart function, left ventricle ejection score and plasma BNP. [Result] In control group, total effective rate was 88.3%; and 98.3 % for treatment group; there's statistical difference between them. [Conclusion] Shenmai injection can improve chronic contractive heart failure patients' heart function, left ventricle ejection score and reduce plasma BNP level.