败酱有效部位PHEBA抗肿瘤作用的研究

摘要

[目的]系统评价有效部位PHEBA的体内、外抗肿瘤作用.[方法]体外培养人源性肿瘤细胞株,利用MTT法、生长抑制曲线、细胞形态学观察,研究PHEBA的体外抗肿瘤作用；利用小鼠移植性肿瘤模型研究PHEBA体内抗肿瘤作用.[结果]PHEBA体外对多个人源性肿瘤细胞株具有抑制作用,体内对小鼠移植性H22肝癌具有抑制作用.[结论]PHEBA体内、外均具有一定的抗肿瘤作用.%[Objective] To study the anti-tumor effects of PHEBA in vivo and in vitro systematically. [Methods] Culture human tumor cell lines in vitro, tornstudy the anti-tumor effects of PHEBA in vitro by MTT assay, growth inhibition curve, cell morphology; By transplanting model of hepatoma 22(H22) inrnmice, Co study the anti-tumor effect in vivo. [Results] PHEBA has anti-tumor effect on various tumor cell lines, it also exhibits effective anti-tumor effect inrnvivo on H22. [Conclusion] PHEBA has certain and-tumor effects in vivo and in vitro.