“疏肝行气,调神解郁”推拿法结合西药治疗腹泻型IBS的临床疗效

摘要

[Objective] To investigate the improvement of abdominal symptoms,quality of life,and depression of "Soothing Liver Regulating Qi and Regulating Spirit and Relieving Depression" massage combined with western medicine treating diarrhea type irritable bowel syndrome(IBS) patients.[Methods] From January 2015 to December 2016,a total of 60 diarrhea type IBS patients were randomly divided into control group and treatment group.The control group was treated with Trimebutine Maleate Dispersible Tablets,while the treatment group was treated with "Soothing Liver Regulating Qi and Regulating Spirit and Relieving Depression" massage on the base of the control group.Two groups patients were treated for 4 weeks.The abdominal symptoms,quality of life,depression and serum 5-HT were collected before and after treatment.[Result] After 4 weeks treatment,the abdominal pain/abdominal discomfort,diarrhea,HAMD of both groups were lower than before treatment,and the treatment group was lower than the control group(P＜0.05).The SF-36 of both groups were higher than before treatment,and the treatment group was higher than the control group(P＜0.05).Serum 5-HT of both groups were lower than before treatment,and the treatment group was lower than the control group(P＜0.05).[Conclusion] "Soothing Liver Regulating Qi and Regulating Spirit and Relieving Depression" massage combined with western medicine can effectively improve the abdominal symptoms and quality of life for diarrhea type IBS patients.%[目的]探讨“疏肝行气,调神解郁”推拿法结合西药对腹泻型肠易激综合征(irritable bowel syndrome,IBS)患者腹部症状、生活质量、抑郁程度的改善情况.[方法]纳入符合标准的腹泻型IBS患者60例,按随机抽签法将患者分为对照组和治疗组.对照组口服马来酸曲美布汀分散片,治疗组在对照组基础上采用“疏肝行气,调神解郁”推拿法,两组患者治疗4周后收集患者治疗前及治疗后的腹部症状、生活质量、抑郁程度及血清5-HT等指标.[结果]治疗后,两组患者腹痛/腹部不适、腹泻、HAMD均较治疗前降低,且治疗组低于对照组,差异均具有统计学意义(P＜0.05);两组患者治疗后SF-36均高于治疗前,且治疗组高于对照组,差异具有统计学意义(P＜0.05);两组患者血清5-HT含量均低于治疗前,且治疗组低于对照组,差异具有统计学意义(P＜0.05).[结论]“疏肝行气,调神解郁”推拿法结合西药治疗能够有效改善腹泻型IBS患者腹部症状及抑郁程度,提高生活质量.