去氧孕烯炔雌醇片预处理联合宫腔镜子宫内膜息肉切除术治疗多发性子宫内膜息肉疗效观察

摘要

目的 探讨去氧孕烯炔雌醇片预处理联合宫腔镜子宫内膜息肉切除术(TCRP)治疗多发性子宫内膜息肉(EP)的疗效.方法 80例多发性EP患者分为2组,观察组43例患者在行TCRP前服用去氧孕烯炔雌醇片1个月,对照组37例患者 在行TCRP前不给予去氧孕烯炔雌醇片,比较2组患者的治疗效果.结果 TCRP术前观察组患者子宫内膜厚度显著小于对照组(P＜0.05).观察组患者手术时间和术后阴道出血时间显著短于对照组(P＜0.05).术后3个月2组患者月经改善率比较差异无统计学意义(P＞0.05).观察组患者EP复发率显著低于对照组(P＜0.05).所有患者均未发生子宫穿孔、出血过多、周围脏器损伤等严重并发症.结论 TCRP术前去氧孕烯炔雌醇片预处理可使子宫内膜厚度明显变薄,缩短手术时间和术后阴道出血时间,降低术后EP复发率.%Objective To observe the effect of desogestrel ethinylestradiol tablet pretreatment combined with transcervical resection of polyp(TCRP) on multiple endometrial polyps(EP).Methods A total of 80 patients with multiple EP were divided into two groups,43 patients in observation group were treated with desogestrel ethinylestradiol tablet for one month before TCRP,but 37 patients in control group were not treated with desogestrel ethinylestradiol tablet pretreatment before TCRP.The effect was compared between the two groups.Results The endometrial thickness in observation group was significantly less than that in control group before operation(P ＜ 0.05).The operation time and vaginal bleeding time in observation group were significantly shorter than those in control group(P ＜ 0.05).There was no significant difference in the improvement rate of menses between the two groups three months after operation (P ＞ 0.05).The recurrence rate of EP in observation group was significantly lower than that in control group(P ＜ 0.05).All patients had no severe complications such as uterine perforation,overmany bleeding and circumambient organs injury.Conclusion Desogestrel ethinylestradiol tablet pretreatment before TCRP can thin the endometrial thickness,shorten operation time and postoperative vaginal bleeding time,and reduce the recurrence rate of EP after operation.