维医异常胆液质证的相关指标特点研究

摘要

Objective To look for characteristics of medical indexes between the abnormal Sapra syndrome group and the non-abnormal Sapra syndrome group for establishing a quantitative Hilit classification stand-ard.Methods Classified the Uygur volunteers who come from CeLe county of Hotan,Xinjiang,and col-lected serum and whole blood samples of the abnormal Sapra syndrome group (n=138)and non-abnormal Sapra syndrome group (n=507).The complete blood count and the blood biochemistry indexes of the two groups were detected by using automatic blood cell analyzer and automatic biochemical analyzer.The dif-ferent indexes were screened and to be done an unconditioned Logistic regression analysis.Results Com-pared with non-abnormal Sapra syndrome group,the WBC,NEU,LEM,HGB,HCT,MCV,CHO, TG,LDL-C of the abnormal Sapra syndrome group were lower,but HDL-C was higher,all the differences were statistically significant (P <0.05),and the HDL-C,LDL-C,LEM and HCT were selected in the re-gression equation basing on multiple logistic regression analysis.Conclusion HDL-C,LDL-C,LEM, HCT may be the indicators to determine abnormal or non-abnormal Sapra syndrome.%目的：探讨异常胆液质证区别于非异常体液质证的医学指标特点，为今后建立量化的体液质分型标准提供依据。方法对新疆和田地区策勒县维吾尔族志愿者进行维医辩证分型，收集645例异常体液质证人群（异常胆液质证组138例，非异常胆液质证组507例）的全血及血清样本，采用全自动血细胞分析仪和全自动生化分析仪检测23项血常规指标和17项生化指标，比较两组各项指标的差异，筛选差异指标进行异常胆液质证与非异常胆液质证相关危险因素的非条件 Logistic 回归分析。结果与非异常胆液质证组相比，异常胆液质证组血常规、生化各指标中白细胞计数（WBC）、中性粒细胞计数（NEU）、淋巴细胞数目（LEM）、血红蛋白（HGB）、红细胞压积（HCT）、平均红细胞体积（MCV）、总胆固醇（CHO）、甘油三酯（TG）、低密度脂蛋白胆固醇酯（LDL-C）水平偏低，高密度脂蛋白胆固醇酯（HDL-C）水平偏高，差异均有统计学意义（P均＜0．05），经多变量 Logistic回归分析，建立回归方程，入选指标有 HDL-C、LDL-C、LEM和 HCT。结论 HDL-C、LDL-C、LEM、HCT 4项指标可成为判断异常胆液质证与非异常胆液质证的指标。