目的：了解内蒙古自治区人民医院2011-2012年临床分离的细菌多重耐药菌的情况。方法采用法国梅里埃 VITEK2/Compect 全自动细菌培养鉴定仪，进行细菌鉴定及药物敏感试验，药敏结果以 CLSI2010版标准进行判读。结果2011年多重耐药菌/泛耐药菌的铜绿假单胞菌（MDR/PDR-PA）检出率为15．7％，2012年为3．1％，检出率呈下降趋势，但两者差异无统计学意义。2011年多重耐药菌/泛耐药菌的鲍曼不动杆菌（MDR/PDR-AB）检出率为32．3％，2012年检出率为16．9％，检出率略有下降但差异无统计学意义。而2011年产超广谱β-内酰胺酶细菌（ESBLs）检出率为27．1％，2012年为64．8％，检出率差异有统计学意义。2011年耐甲氧西林金黄色葡萄球菌（MRSA）检出率64．9％，2012年为69％，差异虽无统计学意义，但仍呈现了高态势 MRSA 的检出率。耐万古霉素金黄色葡萄球菌（VRSA）未检出。结论2012年 MDR/PDR-PA、MDR/PDR-AB 检出率较2011年有下降趋势。ESBLs 检出率呈较明显的上升趋势，而 MRSA 检出率呈较高的态势，VRSA 未检出。%Objective To understand situation of Multidrug-Resistant Organism (MDRO)clinical isolated bacteria from our hospital in the past two years.Methods French merry Emmanuel VITEK2/ Compect automatic bacteria identification instrument was used and judged by standard of CLSI2010Version.Results The detection rate of multi-drug resistant bacteria/pan resistant bacteria of Pseudomonas aeruginosa (MDR/PDR-PA)was 15.7% in 2011,and 3.1% in 2012.The ratio showed downward trend,with no sta-tistical significance.The detection rate of MDR/PDR of Acinetobacter baumannii (MDR/PDR-AB)was 32.3% in 2011,and 16.9% in 2012 .The ratio declined slightly.with no statistical significance.The detec-tion rate of ESBLs was 27.1% in 2011,64.8% in 2012.The difference of detection rate was statistically significant .The detection rate of Methicillin-resistant Staphylococcus aureus(MRSA)was 64.9%,and was 69.0% in 2012.Although the rate had not difference between 2011 and 2012 ,and there was a high de-tection rate of MRSA .Vancomycin resistant Saphylococcus aureus was not detected.Conclusion MDR/PDR-PA and MDR/PDR-AB were decreased in 2012 compared with the condition of 2011.ESBLs was in-creased significantly but MRSA has been presented a higher level all the time.VRSA was not detected for the past two years.
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