AIM: To analyze the influence of maintenance he⁃modialysis on inflammatory markers of senile patients with chronic renal failure. METHODS:A total of 46 patients (>60 years old) with chronic renal failure underwent maintenance hemodialysis ad⁃mitted into No. 85 Hospital of PLA from February 2015 to April 2016 were selected as the experimental group, and 100 healthy people at the same age meanwhile were chosen as the control group. Then the levels of adiponectin, CRP, IL⁃6 on admission day, after 2 weeks after admission, 1 month afrer admission, 2 months after admission in the experimental group were detected, and the level of these inflammatory markers of 100 healthy people were also detected. The level of inflammatory markers between two groups and the level of inflammatory markers before arid after treatment in the experimental group were compared. RESULTS:The adiponectin, CRP, IL⁃6 in the experimental group were all higher then those in the control group( P<0.05);the inflammatory markers of pre⁃hemodialysis in the experimental group were gradu⁃ally higher as time extended, and reached the highest point after 2 months;the inflammatory markers of the experimental group in pre⁃hemodialysis and post⁃hemodialysis weren�t statistically different( P>0.05) . CONCLUSION: The inflammatory status of senile patients with chronic renal failure can�t be reduced by maintenance hemodialysis, and anti⁃inflammatory therapy is necessary for clinical treatment.%目的：分析维持性血液透析治疗对老年慢性肾功能衰竭患者炎症标志物的影响．方法：选取2015－02／2016－04于中国人民解放军第八五医院进行维持性血液透析的年龄＞60岁的慢性肾功能衰竭患者46例作为研究对象，设为实验组，并选取同期于中国人民解放军第八五医院进行体检的100例＞60岁的健康者设为对照组．实验组选择入院时、2周后、1个月后、2个月后等时间点分别检测患者进行血液透析前后的血清脂联素、C反应蛋白（CRP）、白介素⁃6（IL⁃6）等炎症标志物水平，对健康受试者也进行血清脂联素、CRP、IL⁃6水平检测，比较两组炎症标志物水平及实验组治疗前后炎症标志物的变化情况．结果：实验组血清脂联素、CRP、IL⁃6等水平均高于对照组，差异具有统计学意义（P＜0．05）；实验组入院时、2周后、1个月后、2个月后的透析前、透析后各炎症标志物水平比较，差异无统计学意义（ P＞0．05）；随着时间的延伸，实验组患者炎症指标不断升高，入院时、2周后、1个月后、2个月后的透析前各炎症标志物水平比较，差异具有统计学意义，2个月后最高，差异有统计学意义（P＜0．05）．结论：老年肾衰竭患者进行维持性血液透析不能降低脂联素、CRP、IL⁃6等水平，提示临床有必要进行抗炎治疗．
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