以乙醇、乙醇/水为溶剂提取白桦树皮中桦木醇的工艺研究

摘要

分别以乙醇、乙醇/水、水为提取剂,研究从白桦树皮中提取桦木醇的工艺,确定了用乙醇作提取剂的最佳提取工艺条件:固液比(g:mL)为0.083,抽提时间6h;分别用异丙醇和乙醇作溶剂,通过两步重结晶操作,纯化桦木醇,得到桦木醇产品的产率达19.8％,熔点257.7～258.9℃,纯度98％.%The technological conditions for extraction of betulin from the outer bark of white birch were investigated. Etha-nol, ethanol/water and water were used as extraction solvents. The suitable extraction conditions were determined for extraction of betulin with ethanol as extraction solvent as follows: ratio of solid to liquid was 0.083, extraction time 6 h. Crude betulin was puritied and high purity produce was obtained by two step recrystallization. The yield of betulin reached 19.8%, melting point was 257.7-258.9 ℃, and the purity was 98%.