Method of preparation and isolation of betulin diacetate from birch bark from paper mills and its optional processing to betulin

摘要

described method preparation and isolation of betulin with brezovu00e9 cortex from paper mills and his pru00edpadnu00e9ho processing on betulin by brezovu00e1 kura is ground.after mixed with a two - or dvacetinu00e1sobnu00fdm volume of water, and mix, so that all brezovu00e1 kura was smocena, then he has the proportion of brezovu00e9 cortex, floating on the surface.the proportion of brezovu00e9kury collected dry at temperature in the range of 50 to 85.degree.c and then subjected to brezovu00e9 betulin contained in dried chicken acetylaci, after acetylaci is brezovu00e1 kura dried at temperature in the range of 50 to 100.degree.c and the betulin diacetate is then isolated zbrezovu00e9 cortex superkritickou extraction brezovu00e9 kuryoxidem uhlicitu00fdm for pressure of 28 - 35 mpa and temperatures of 50 - 100.degree.c and figure below is superkriticku00fd extract prekrystalizuje for direct use or further processing. further processing may be basis hydrolysis prekrystalovanu00e9ho betulin with the betulin.