目的 探讨糖尿病足溃疡的超声造影灌注动态变化.方法 研究16例糖尿病足溃疡的常规及超声造影图像,分析其造影增强的图像特点,并对部分病例进行病理检查.结果 注射SonoVue后,16个病灶超声造影动脉期清晰显示随时间推移呈缓慢增强,平均开始增强时间为(30.02+2.35)s,达峰时间为(37.54-4.13)s.5例呈均匀增强区域,11例呈周边较均匀增强,内部可见片状无增强区域,即液化坏死区.造影提示病灶范围较常规超声范围大.结论 超声造影能有效地对糖尿病足溃疡进行范围评估和治疗随访.%Objective To investigate contrast-enhanced ultrasound imaging features of diabetic foot ulcers. Methods Sixteen patients with diabetic foot ulcers underwent conventional and contrast-enhanced ultrasound examinations, and the features of contrast-enhanced ultrasound imaging were analyzed. Pathological examination was also carried out in some cases. Results Contrast-enhanced ultrasound showed slow enhancement in the artery phase in the 16 ulcers after administration of SonoVue. The mean time of initial enhancement was 30.02±2.35 s, and the mean time for the occurrence of peak enhancement was 37.54± 4.13 s. In 5 cases a homogeneous enhancement pattern was clearly displayed, and in the other 11 cases, a pattern of homogenous peripheral enhancement with non-enhanced patches within the ulcers was found. Contrast-enhanced ultrasound showed a greater ulcerous area than conventional ultrasound. Conclusion Contrast-enhanced ultrasound is a valuable means for evaluating the ulcerous area and the treatment efficacy for diabetic foot ulcers.
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