Objective:To evaluate the clinical characteristics of diabetic patients with acute myocardial infarction and the incidence of MACE after being treated with drug-eluting stents .Methods:350 patients who presented with acute myocardial infarction and were treated with drug-eluting stents were classified into 2 groups according to the presence or absence of DM .The clinical characteristics and one-year follow-up results in the two groups were analyzed.Results:The patients with DM were older than the patients without DM [(65.50 ±12.73)vs(60.80 ± 14.38),P=0.004].The ratio of male patients was lower in the DM group (58.5%vs 70.1%,P=0.012)and the ratio of smoking ( 38.3% vs 24.3%, P =0.007 ) , hypertension ( 84.1% vs 76.1%, P <0.001 ) , hyperlipidemia (89.7%vs 79.0%,P=0.016),chronic renal insufficiency (24.3% vs 8.2%,P<0.001) was higher in the DM group.The incidence of multi-vessel disease was higher in the DM group (41.1%vs 29.6%,P=0.035) ,but the incidence of one-vessel disease was higher in the non-DM group (27.1%vs 44.4%,P=0.002).The incidence of composite MACE of one year was higher in the DM group (19.6%vs 9.5%,P=0.008).The incidence of death of one year was higher in the DM group (13.1% vs 4.5%,P=0.004).Conclusion: The DM patients with AMI is older and have higher ratio of female gender ,smoking,hypertension,hyperlipidemia and chronic renal insufficiency than the non-DM patients with AMI;Compared to the non-DM patients with AMI ,the DM patients with AMI show a preponderance of multi-vessel disease , the drug-eluting stent does not increase the incidence of myocardial infarction,target lesion revascularization , restenosis and stent thrombosis in the DM group .The incidence of composite MACE of one year is higher in the DM group , the all-case death are the dominant event .%目的：探讨糖尿病急性心肌梗死患者的临床特点，分析植入药物洗脱支架后1年的随访情况。方法：将入选的350名急性心肌梗死患者分为两组，其中糖尿病组107人，非糖尿病组243人。所有患者均植入药物洗脱支架，对两组患者的临床危险因素及1年随访结果进行分析。结果：糖尿病组比非糖尿病组患者年龄大[（65.50±12.73）vs（60.80±14.38）岁，P＝0.004]、男性比例少（58.5％ vs 70.1％，P＝0.012）、吸烟比例高（38.3％ vs 24.3％，P＝0.007），更易合并高血压病（84.1％ vs 76.1％，P＜0.001）、高脂血症（89.7％vs 79.0％，P＝0.016）、慢性肾功能不全（24.3％vs 8.2％，P＜0.001）等情况。糖尿病组比非糖尿病组3支病变比例高（41.1％vs 29.6％，P＝0.035）、单支病变比例低（27.1％vs 44.4％，P＝0.002）。糖尿病组主要心脏不良事件总的发生率高于非糖尿病组（19.6％vs 9.5％，P＝0.008），其中全因性死亡是主导事件（13.1％vs 4.5％，P＝0.004）。两组患者靶病变血运重建（4.7％ vs 4.5％， P＝0.952）、靶血管血运重建（12.1％vs 7.8％，P＝0.195）、再次心肌梗死（1.9％ vs 0.4％，P＝0.173）、支架内再狭窄（2.8％ vs 2.9％， P＝0.968）、支架内血栓形成（1.9％vs 1.6％，P＝0.882）的发生率没有显著差异。结论：糖尿病急性心肌梗死患者比非糖尿病急性心肌梗死患者平均年龄大，且女性、吸烟、高血压、高血脂、肾功能不全、3支病变的比例均高于后者，药物洗脱支架没有增加糖尿病急性心肌梗死患者再次心肌梗死、血运重建、支架内再狭窄、支架内血栓形成的发生率，但其主要心脏不良事件总的发生率比非糖尿病急性心肌梗死患者高，且主导事件是全因性死亡。
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