长白狗舌草化学成分研究

摘要

采用硅胶柱色谱、Sephadex LH-20柱色谱等方法对长白狗舌草分离纯化，根据理化性质和波谱数据进行结构鉴定。分离并鉴定了5个化合物，分别为二十四烷酸（1），十六烷酸单甘油酯（2），α-棕榈酸单甘油酯（3），β-谷甾醇葡萄糖苷（4）和齐墩果酸（5）。化合物1~5均为首次从长白狗舌草中分离得到。%Chemical constituents of Tephroseris phaeantha were isolated by column chromatography and semi-prepared HPLC,the structures were elucidated of spectral data and physical-chemical properties.Five compounds were isolated and respectively identified as tetracosanoic acid(1),daturic acid 2,3-dihydroxypropyl ester(2),α-palm acid monoglyceride(3),β-sitosterol-glucopyranoside(4),Oleanolic acid(5).Compound 1~5 are isolated from Tephroseris phaeantha for the first time.