Objective: To explore the indication of whole embryos freezing for patients with polycystic ovary syndrome ( PCOS ) in in-vitro fertilization/intracytoplasmic sperm injection-embryo transfer OVF/ICSI-ET).rnMethods: The data of 1,773 long protocol cycles for PCOS patients who underwent IVF/ICSI-ET from Jan. 2009 to Dec. 2011 were analyzed retrospectively in Hospital for Reproductive Medicine, Provincial Hospital Affiliated to Shandong University. The patients were divided into two groups, the whole embryos freezing group (343 cycles) and the fresh embryos group (1,430 cycles). Besides, they were divided into four subgroups according to the occurrence of moderate or severe ovarian hyper-stimulation syndrome (OHSS). The women in Subgroup A suffered from OHSS after whole embryos freezing procedure (67 cycles), while women in Subgroup B did not (276 cycles). Furthermore, the patients in Subgroup C suffered OHSS after fresh embryos transfer (22 cycles) while patients in Subgroup D did not (1408 cycles). Main outcome measures such as the duration of gonadotrophin administration, the number of oocytes retrieved, the estradiol (E2 ) levels after hCG injection, the number of frozen embryos, clinical pregnancy rate and OHSS incidence were compared among these groups mentioned above.rnResults: (1). The OHSS incidence of fresh embryos group (1. 5%) was significantly lower than the whole embryos freezing group (19. 5%)(P<0. 01). The clinical pregnancy rate (57%) in fresh embryo transfer group was lower than that in the frozen embryos transfer group (P展开▼
