颈内动脉狭窄支架置入血管成形术后发生再灌注损伤的临床分析

摘要

Objective To investigate the internal carotid artery stenosis stenting factors postoperative reperfusion injury in shape. Methods In our hospital from January 2014 to March 2016 35 hospitalized patients with carotid artery stenosis stenting in patients undergoing shaping as a research object. In accordance with internal carotid artery stenosis as severe stenosis group and 15 cases of 20 patients with moderate stenosis. Two groups of patients were treated with internal carotid artery stenosis stent angioplasty, the two groups after statistical probability of reperfusion injury and inlfuencing factors.Results The rate of reperfusion injury in patients with severe stenosis was signiifcantly higher in patients, the difference was statistically signiifcant (P<0.05). Internal carotid artery stenosis stenting angioplasty main factors of postoperative reperfusion injury incidence for age, comorbidities and stenosis patients.Conclusion Based on the internal carotid artery stenosis stent angioplasty reperfusion injury risk of the occurrence of postoperative factors and statistical analysis, patient age, comorbidities and other factors stenosis greater chance of postoperative reperfusion injury affected.%目的：探讨颈内动脉狭窄支架置入血管成形术后发生再灌注损伤的影响因素。方法选取我院从2014年1月到2016年3月入院治疗的35例颈内动脉狭窄支架置入血管成形术患者做为研究对象。按照患者颈内动脉狭窄程度分为重度狭窄组15例与中度狭窄组20例。两组患者均采用颈内动脉狭窄支架置入血管成形术治疗，统计两组患者术后再灌注损伤几率及影响因素分析。结果重度狭窄组患者的再灌注损伤率显著高于对照组患者，差异具统计学意义(P＜0.05)。颈内动脉狭窄支架置入血管成形术后再灌注损伤发生率的主要影响因素为患者的年龄、合并疾病及狭窄程度。结论通过对颈内动脉狭窄支架置入血管成形术后发生再灌注损伤的发生几率及其影响因素统计分析，患者年龄、合并疾病及狭窄程度等因素对于术后再灌注损伤几率影响较大。