老年女性骨质疏松症患者血清BGP、CT、E2、Ca和P检测的临床意义

摘要

Objective To explore the clinical significance of measuring the changes of serum BGP,CT, E2 ,Ca and P levels in patients with elderly women osteoporosis. Methods Serum BGP, CT, E2(with RIA) , serum Ca,P (with biochemistr) levels were measured in patients with elderly women osteoporosis and compared to 35 normal healthy women as controls. Results Serum BGP, CT, E2 levels were significantly lower than those in controls(P<0.01). But serum Ca,F levels showed notably higher than the con-trols(P<0.01). Serum BGP level expressed positively correlated with CT, E2 levels(r =0.4825,0.5018,P<0.01). Serum BGP level indicated negatively correlated with Ca,P levels (r = -0.6144, -0.4786,P<0.01). Conclusion The chages of above laboratory i-tems provides valuable date for clinical diagnosis and treatment in patient with elderly women osteoporosis.%目的:探讨了老年女性骨质疏松症患者血清BGP、CT、E2、Ca和P水平的变化及临床意义.方法:应用放射免疫分析和生化法对32例老年女性骨质疏松患者进行了血清BGP、CT、E2、Ca和P检测,并与35名正常健康老年女性进行比较.结果:老年女性骨质疏松症患者血清BGP、CT、E2水平显著地低于正常老年女性组(P<0.01),而血清Ca和P水平又明显高于正常老年女性组(P<0.01),且血清BGP水平与CT、E2水平呈正相关(r=0.4825、0.5018,P<0.01),而与Ca、P水平呈显著负相关(r=-0.6144、-0.4786,P<0.01).结论:检测老年女性骨质疏松症患者血清BGT、CT、E2、Ca和P水平的变化,可为临床诊断和治疗提供一个有价值的数据.