新型亚锡－氟化钠牙膏和交叉刷毛牙刷减轻牙龈炎和清除牙菌斑效果研究

摘要

Objective:To investigate the effects of a stannous-containing sodium fluoride dentifrice and crisscross bristle manual tooth-brush in the management of dental plaque and gingivitis.Methods:249 cases with gingivitis were enrolled in an office-based study. The study was unsupervised and single-centered with open-label and self-control.At baseline,gingival health and plaque coverage were assessed by dentists using categorical scales.Participants were given stannous containing sodium fluoride dentifrice and crisscross bristle design manual brush,and were instructed to use the products by manufacturer's usage instructions twice daily for 30 days.At the end of 30 days,plaque and gingivitis were reassessed using the same categorical scales.Results:232 participants(1 78 females and 54 males) completed the study.Gingivitis data of 5 cases and dental plaque data of 3 cases were not judgable.After 30 days of product use,226 cases(99%)showed noticeable improvement in their gingival health;227(96%)cases showed improvement in overnight plaque cover-age.Conclusion:Stannous-containing sodium fluoride dentifrice in combination with crisscross bristle toothbrush is effective in the management of gingivitis and dental plaque.%目的：观察新型亚锡－氟化钠牙膏和交叉刷毛牙刷减轻牙龈炎和清除牙菌斑效果。方法：纳入中度和重度牙龈炎及牙菌斑覆盖受访者，采用开放标签、单中心、自身前后对照试验。按厂家说明使用含亚锡－氟化钠系统的牙膏和交叉刷毛的牙刷每日刷牙2次，为期30 d。由专业牙科医师对受访者的牙龈健康和牙菌斑覆盖程度进行基线和终点标准化的评估。结果：纳入符合标准的受访者249名，平均年龄（31．37±7．24）岁。女性185名，男性64名。232名受访者完成了研究。5人牙龈炎数据不可评估，3人牙菌斑数据不可评估，226名（99％）受访者牙龈炎明显减轻，227名（96％）受访者隔夜牙菌斑显著减轻。结论：使用新型亚锡－氟化钠牙膏和交叉刷毛牙刷可以抑制牙菌斑的形成和减轻牙龈炎。