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Fluoride releasing from Dental Pit and Fissure Sealant including Sodium Fluoride and Stannous Fluoride

机译:牙槽和缝隙密封剂中的氟化物释放,包括氟化钠和氟化亚锡

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The 2% NaF and 8% SnF_2 have been used in topical fluoridation method in the dental office to increase the resistance of enamel to acid dissolution. Bis-GMA based monomers have been used for the basic materials in the dental pit and fissure sealants. Therefore, the resinous pit and fissure sealant including fluorides may increase the effect of preventing dental caries. In this study, we made a novel dental pit and fissure sealant and evaluated some properties, especially fluoride release. In order to make experimental pit and fissure sealant including fluoride, NaF and SnF_2 powder were added into self-made monomer composed of Bis-GMA, TEGDMA, UDMA and photo initiator system by weight percent of 2% and 8% respectively. The just monomer without fluoride powder was used for control. Uncured film thickness and depth of cure were measured according to ISO specification 6874:1988 and the viscosity was measured using rheometer. The five disc specimens were made using light curing unit to evaluate fluoride releasing and each specimen was immersed in the artificial saliva of 10 mL. Fluoride ion concentrations in extracts were measured for 3 days using fluoride electrode at every 12 hrs. There was no significant difference between experimental and control group in the depth of cure, uncured film thickness, and viscosity (p>0.05). The released fluoride ion concentration was continuously retained for 72 hrs.
机译:2%NaF和8%SnF_2已用于牙科诊所的局部氟化方法中,以提高牙釉质对酸溶解的抵抗力。基于Bis-GMA的单体已被用作牙坑和裂隙密封胶中的基础材料。因此,包含氟化物的树脂凹坑和裂缝密封剂可提高预防龋齿的效果。在这项研究中,我们制作了一种新型的牙坑和裂隙密封剂,并评估了一些性能,尤其是氟化物的释放。为了制备包括氟化物的实验性凹坑和裂缝密封剂,将NaF和SnF_2粉末分别添加到Bis-GMA,TEGDMA,UDMA和光引发剂体系组成的单体中,其重量百分比分别为2%和8%。不含氟化物粉末的纯单体用于对照。根据ISO规范6874:1988测量未固化的膜厚度和固化深度,并使用流变仪测量粘度。使用光固化装置制作五个圆盘标本,以评估氟化物的释放,并将每个标本浸入10 mL的人造唾液中。每隔12个小时使用氟化物电极对萃取物中的氟离子浓度进行3天的测量。实验组和对照组之间在固化深度,未固化膜厚度和粘度方面无显着差异(p> 0.05)。释放的氟离子浓度连续保持72小时。

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