Objective To investigate the correlation between DWI value of cervical cancer in stage Ib1-II A2 and its pelvic lymph node metastasis. Methods 103 patients with cervical cancer of stage Ib1 - IIa2 confimed by surgery and pathology in our hospital from January 2014 to July2016 were retro-spectively studied,78 cases of cervical squamous cell carcinoma group(lymph node metastasis of 22 cases,non- lymph node metastasis 56 cases);25 cases of Cervical adenocarcinoma group(9 cases with lymph node metastasis,16 cases of no lymph node metastasis). All patients with preoperative were performed MR routine scan and DWI examination. The ADC value(meanADC,minADC and maxADC)between the two groups and between the groups with and without metastasis were statistically analyzed. Results The value of ADC staging of cervical carcinoma had no correlation with clinical FIGO stage(Pmean = 0.847、Pmin = 0.393、Pmax = 0.219). The meanADC values、minADC value、maxADC value[(0.84 ± 0.09)× 10-3mm2/s、(0.78 ± 0.09)× 10-3mm2/s、(0.86 ± 0.07)× 10-3 mm2/s]of Squamous cell carcinomas was lower than that of adenocarcinoma[(0.98 ± 0.04)× 10-3mm2/s、(0.93 ± 0.09)×10-3mm2/s、(0.97 ± 0.23)× 10-3mm2/s]and the difference was statistically significant(P <0.05). The meanADC values and minADC value of cervical cancer within each group in lymph node metastasis group was lower than that of non- lymph node metastasis group,the difference was statistically significant(P <0.05). The maxADC value had no significant difference(P > 0.05). Conclusion The ADC value of cervical cancer has some correlation with lymph node metastasis,which can be helpful to predict the risk of lymph node metastasis.%目的 探讨Ⅰb1~Ⅱa2期宫颈癌的DWI值与其在盆腔淋巴结转移中的相关性.方法 回顾性分析于2014年1月至2016年7月行手术并病理证实的103例Ⅰb1~Ⅱa2宫颈癌患者的病例资料,宫颈鳞癌78例(淋巴结转移22例,非淋巴结转移56例),宫颈腺癌组25例(淋巴结转移9例,非淋巴结转移16例).患者在术前均行MR检查.分别对两组间、各组内转移与非转移病灶组间表观弥散系数ADC值(meanADC、minADC、maxADC)进行统计学分析.结果 宫颈癌各ADC值与临床FIGO分期均无相关性(Pmean=0.847、Pmin=0.393、Pmax=0.219);鳞癌meanADC值、minADC值、maxADC值[(0.84 ± 0.09)×10-3 mm2/s、(0.78 ± 0.09)×10-3mm2/s、(0.86 ± 0.07)×10-3mm2/s]均低于腺癌各ADC值[(0.98 ± 0.04)×10-3mm2/s、(0.93 ± 0.09)×10-3mm2/s、(0.97 ± 0.23)×10-3mm2/s],差异具有统计学意义(P<0.05);各组内淋巴结转移组meanADC值、minADC值均低于非淋巴结转移组,差异具有统计学意义(P<0.05),而两者maxADC值无统计学差异(P>0.05).结论 宫颈癌病灶的ADC值与淋巴结转移具有一定相关性,可有助于预测淋巴结转移的风险.
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