肝硬化并发细菌感染诊断与治疗研究进展

摘要

细菌感染是肝硬化患者常见的并发症,一旦出现感染,病情容易进展为肝衰竭和多器官功能衰竭而死亡.肝硬化并发细菌感染早期不易发现,缺乏敏感性及特异性较高的诊断办法.另外,近年来细菌耐药性的不断增加,使得肝硬化并发细菌感染的发病率及病死率仍处于较高的水平.本文重点介绍了肝硬化患者并发细菌感染的临床类型、细菌谱变化、诊断的难点和目前的治疗策略.%Bacterial infection is a common complications in patients with liver cirrhosis. Once the patients with liver cirrhosis got bacterial infections,the disease might progress quickly to liver failure,multiple organ failure and the mortality was high,which might be due to latent onset,difficult early diagnosis and the growing spread of multi-resistant pathogens. In this reviews,we will take focus on the clinical types of infections, the consequences of infections,the changes of bacterial spectrum, and the strategies in diagnosis and the current treatment.