怀旧疗法对阿尔茨海默症患者认知功能及生活质量的影响

摘要

Objective To explore the influence of nostalgic therapy on cognitive function and quality of life (QOL) of patients with Alzheimer’s disease. Methods Six-eight patients with Alzheimers’s disease were divided into control group and intervention group with 34 patients in each group. Patients in control group received conventional medications, health education and cognitive intervention while those in intervention group received 8-week nostalgic therapy in addition to the interventions conducted in control group. Mini-mental State Examination (MMSE) and the Quality of Life-Alzheimer Disease (QOL-AD) scale were applied before and after the intervention. Results There was no statistical significance of the score of MMSE and QOL-AD scale before the intervention. After 8-week intervention, the score of MMSE in intervention group (21.12±3.32) and that in control group (16.82±3.26) and the score of QOL-AD scale in intervention group (28.12 ±3.52) and that in control group (19.29 ±3.16) indicated statistical significance (t=3.75, P<0.01 and t=11.35, P<0.01 respectively). Conclusion Nostalgic therapy is effective for promoting cognitive funtion and QOL of patients with Alzheimer’s disease.%目的：探讨怀旧疗法对阿尔茨海默症患者认知功能及生活质量的影响。方法将68例阿尔茨海默症患者按照住院号单双号分为干预组和对照组，各34例。对照组接受常规药物治疗、健康教育和认知干预，干预组在此基础上，实施为期8周的怀旧疗法。干预前、后分别采用简易精神状态量表和老年痴呆生活质量量表进行评定。结果干预前，2组简易精神状态、老年痴呆生活质量得分比较，差异均无统计学意义。干预8周，对照组简易精神状态（16.82±3.26）分，干预组（21.12±3.32）分，差异有统计学意义（t=3.75，P<0.01）。干预8周，对照组老年痴呆生活质量（19.29±3.16）分，干预组（28.12±3.52）分，差异有统计学意义（t=11.35， P<0.01）。结论怀旧疗法可有效提高阿尔茨海默症患者的认知功能和生活质量。