Objective To study the effect of cluster-based nursing for digestive tract toxins cleaning for the treatment of acute severe organophosphorus poisoning patients. Method 46 patients with acute severe organophosphorus poisoning from July 2009 to June 2011 were selected for the study. All patients using the left lateral position and applying 0. 008% concentration of norepinephrine by porous tube gastric lavage. The esophagus tube and oral cavity cleaning, repeated gastric lavage indwelling stomach tube gastric lavage was used. Early cathartic and enema were used simultaneously. 33 cases given routine nursing was selected as control group from Jan 2008 to June 2009. To compare the distinction in the clearing time of intestinal tract, atropinization, intermediate syndrome and CHEs recovery, the hospital days and the cost of hospitalization between the two groups. Result Compared with the control group, cluster-based nursing obviously decreased the clearing time of intestinal tract atropinization and CHEs recovery, intermediate syndrome, hospital days and the cost of hospitalization (P<0. 05). Conclusion cluster-based nursing of digestive tract toxins cleared have beneficial effects for acute severe organophosphorus poisoning therapy.%目的 探讨早期消化道毒物清除的集束化护理对急性重度有机磷中毒治疗效果的影响.方法 对2009年7月～2011年6月我科诊治的46例急性重度有机磷中毒患者进行集束化护理(集束化护理组),所有患者均采用左侧卧位,配制0.008％浓度的去甲肾上腺素洗胃液,选用多孔洗胃管,并增加食管、口腔的清洗,留置胃管反复洗胃,早期导泻和灌肠等集束化护理措施；选取我科2008年1月～2009年6月诊治的33例按常规护理的急性重度有机磷中毒患者为对照组.比较两组患者间清洁肠道时间、阿托品化时间、发生中间综合征的例数、CHE恢复正常时间、住院天数、住院费用的差异.结果 与常规护理组相比,集束化护理组患者清洁肠道时间、阿托品化时间、发生中间综合征的例数、CHE恢复正常时间、住院天数及住院费用明显降低,P＜0.05.差异均有显著意义.结论 早期消化道毒物清除的集束化护理,可明显缩短急性重度有机磷中毒患者清洁肠道时间、阿托品化时间及CHE恢复正常时间,减少中间综合征的发生,提高了抢救成功率,降低治疗成本,具有良好的经济和社会效益.
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