女贞子提取物对运动训练大鼠不同组织抗氧化酶活性及GSH含量影响

摘要

通过建立大鼠递增大强度耐力跑台训练试验模型,测定大鼠力竭时间和抗氧化酶活性及GSH含量影响.结果表明,女贞子提取物可增加力竭运动状态下铜、锌超氧化物歧化酶(Cu-Zn-SOD)、锰超氧化物歧化酶(Mn-SOD)、谷光甘肽过氧化物酶(GSH-Px)活性及还原性谷胱甘肽(GSH)含量.可见补充女贞子提取物可显著提高大鼠各组织抗氧化酶活性,减轻力竭运动对大鼠各组织造成脂质过氧化损伤,具有明显抵抗脂质过氧化功能,对大鼠运动能力提高有良好作用.%The thesis aimed at investigating the effects of Ligustrum lucidum extracts on different organizational activities of exhaustive exercise in rats,its antioxidant and the possible mechanisms of improving the body's resistance to fatigue.The experimental model of increasing endurance treadmill training in rats,was established,and the exhaustive time,antioxidant enzyme activities and GSH content in rats were measured.The results showed that Ligustrum lucidum extract increased copper,zinc superoxide dismutase (Cu-Zn-SOD),manganese superoxide dismutase (Mn-SOD),glutathione peroxidase (GSH-Px)activity and reduced glutathione (GSH) content of different organizations in exhaustive exercise rats.Supplementary with Ligustrum lucidum extracts significantly increased antioxidant enzyme activity,reduced lipid peroxidation damage caused by exhaustive exercise and lipid peroxidation of organization in rats,and played a good role in improving athletic capacity in rats.