首页> 中文期刊> 《北方药学》 >丙泊酚和七氟烷在患儿全身麻醉中对血流动力学、术后苏醒质量的影响对比研究

丙泊酚和七氟烷在患儿全身麻醉中对血流动力学、术后苏醒质量的影响对比研究

         

摘要

Objective: To evaluate the propofol and sevoflurane in children with general anesthesia applications. Methods: Our hospital 180 cases of children with inguinal hernia elective surgery were randomly divided into propofol group and sevoflurane anesthesia group, 90 cases. Continuous monitoring of children with systolic blood pressure(SBP), heart rate(HR), electrocardiogram(ECG), diastolic blood pressure(DBP), the depth of anesthesia(BIS), oxygen saturation(SpO2), PETCO2. Record children after induction of anesthesia (T1), before induction (T0), endotracheal intubation (T2), 3min (T3), when the procedure is complete (T4), when the eyes open (T5), fully awake after intubation (T6) of SBP, HR, DBP, BIS. Results: The two groups were compared in the index, systolic and diastolic blood pressure significantly decreased compared with the induced (P<0.05), sevoflurane group of children surgery extubation time and postoperative recovery time after the completion of induction of anesthesia compared with propofol group was significantly shorter(P<0.05). Conclusion:propofol and sevoflurane anesthesia can effectively lower blood pressure, heart rate stability, to maintain a considerable depth of anesthesia, sevoflurane awake but better quality.%目的:评价丙泊酚与七氟烷在患儿全身麻醉中的应用效果。方法:选择我院择期手术的180例腹股沟斜疝患儿,随机分为丙泊酚麻醉组和七氟烷麻醉组各90例。连续监测患儿收缩压(SBP)、心率(HR)、心电图(ECG)、舒张压(DBP)、麻醉深度(BIS)、血氧饱和度(SpO2)、PETCO2。记录患儿麻醉诱导后(T1)、诱导前(T0)、气管插管即刻(T2)、插管后3min(T3)、手术完成时(T4)、睁眼时(T5)、完全清醒时(T6)的SBP、HR、DBP、BIS。结果:两组患儿组内各指标相比,麻醉诱导后收缩压和舒张压与诱导前比较明显下降(P<0.05),七氟烷组患儿手术完成时拔管时间和术后苏醒时间与丙泊酚组相比,显著缩短(P<0.05)。结论:丙泊酚与七氟烷麻醉均能有效降压,稳定心率,维持相当的麻醉深度,但是七氟烷苏醒质量更好。

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