鼻内镜手术后使用帕瑞昔布钠控制疼痛的研究

摘要

Objective: Nasal endoscopic surgery using parecoxib sodium control pain were performed to study the effect of, for clinical analgesic provide theoretical basis. Methods: A total of 2014 may to August 2015 to our hospital underwent nasal endoscopic surgery in treatment of 80 cases of patients as the research object, in accordance with the principle of randomized, double blind, the patients were divided into two groups, namely, the control group (40 cases) after surgery do not take analgesic drug, and the observation group(40 cases) taking parecoxib sodium on postoperative analgesia, using a pain visual analogue score table (VAS) of two groups of patients with postoperative pain scores of different periods to be evaluated and compared two groups of patients with adverse reaction incidence. Results: 8h, 24h postoperative stages, the two groups of patients with pain remained the same, the data showed no significant difference; postoperative 24h, 48h time observed groups of patients with pain score was significantly lower than that of the control group, the data difference significant (P<0.05). Conclusion:After nasal endoscopic surgery use analgesia with parecoxib sodium, can effectively control the pain caused by nasal endoscopic surgery trauma sense, recommended to use in clinical practice.%目的：对鼻内镜手术后使用帕瑞昔布钠控制疼痛的效果进行研究，为临床镇痛提供理论依据。方法：选取2014年5月～2015年8月来我院接受鼻内镜手术治疗的80例患者为研究对象，按照随机双盲原则将患者分成两组，即对照组（40例）术后不采取镇痛药镇痛，观察组（40例）采取帕瑞昔布钠进行术后镇痛，使用疼痛视觉模拟评分量表（VAS）对两组患者术后不同时段的疼痛评分予以评价，对比两组不良反应发生情况。结果：术后8h、24h等阶段两组患者疼痛程度基本保持一致，数据差异不明显；术后24h、48h两个时段观察组疼痛评分显著低于对照组，数据差异显著（P＜0.05）。结论：鼻内镜手术后使用帕瑞昔布钠镇痛，能够有效控制因鼻内镜手术创伤引起的疼痛感，建议在临床上推广。