Vesical calculus are more commonly seen in males than female counterparts.Giant vesical calculus with a diameter >5 cm is extremely rare in females.We reported a female case of giant vesical calcu-lus complicated with chronic renal insufficiency,secondary epilepsy and urinary infection.Furthermore,the causes of diseases,clinical symptoms and therapeutic regimen were investigated based upon clinical character-istics,and relevant literatures were retrospectively reviewed.This female case hinted that much attention should be paid to giant vesical calculus because it is easily neglected due to reclusive symptoms.Moreover,it yields a high incidence of spontaneous rupture of the bladder and related complications.%膀胱结石多见于男性患者,女性患者中直径>5 cm 的巨大膀胱结石罕见。该文报道了1例女性巨大膀胱结石合并慢性肾功能不全、继发性癫痫和泌尿系感染患者,并根据其临床特点对该例无症状型混合性巨大膀胱结石的成因、临床症状和治疗方案进行了探讨以及相关文献的回顾,该例提示巨大膀胱结石症状隐匿,易于疏忽,加上其可引起自发性膀胱破裂,且并发症发生率高,应引起临床重视。
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