当归对蛙心脏活动的影响

摘要

The aim of this study was to study the effect of Angelica sinennsis on toad heart activates. Using toad as experiment animal, we tested the heart rate, maximal cardiac contractility, mean cardiac contractility, and cardiac electric by BL-410 biological functional system in each four groups. Results showed that sinennsis had no effect on toad heart rate, but had obvious inhibition on maximal cardiac contractility, mean cardiac contractili-ty and cardiac electric. The index was increased first and then decreased with the increase amount of Angelica tablets. There was a significant positive correlation between cardiac contractility and cardiac electric. Based on the results, our conclusion was as follows:the kind of traditional Chinese medicine has no obvious effect on heart rate. However, it had effect on cardiac contractility and cardiac electric. With appropriate amount, it can protect heart from the myocardial ischemia, heart failure, etc.%为了研究当归对蟾蜍在体心脏活动功能的影响，以蟾蜍为实验动物，利用BL-410生物机能实验系统，以蟾蜍心率、心搏最大收缩力、心搏平均收缩力和心肌电为指标，该药分设四个实验组进行实验。结果表明：当归片对蟾蜍心率没有显著影响，对蟾蜍心搏最大收缩力、心搏平均收缩力和心肌电产生显著影响，随当归片灌胃量的增加，先增大后减小。心搏收缩力与心肌电表现出显著的正相关性。由此获得基本结论：当归对心率基本无显著影响，但对心脏的收缩力和心肌电有影响，适当的用量有利于改善心肌功能，在心肌缺血损伤、心力衰竭情况下，有利于保护心脏。