动脉硬化是心血管疾病的主要危险因素.糖化终产物则是导致动脉发生硬化的原因之一,它使得动脉基质中的胶原蛋白产生交互连结,造成动脉壁延展性降低而导致动脉发生硬化.糖化终产物的形成,与氧化压力有很大的关系,而氧化压力又与生活中压力所导致的情志不畅,以及饮食型态、生活习惯有关.对于动脉硬化,中医的治疗与护理原则多以活血化瘀、软坚散结为主,依据辨证的基础,给予相应的治疗及护理措施.%One of the major risk factors for cardiovascular disease is arterial stiffness.There are several mechanisms associated with the development of arterial stiffness,including the involvement of advanced glycation end products.Arterial stiffness results from altered distensibility of arterial walls and is associated with advanced glycation end product-related cross-linking of collagen in the artery matrix.Oxidative stress is associated with advanced glycation end products formation and triggered by moodiness,feeding mode,and lifestyle.In TCM and care,the major treatment for arterial stiffness includes activating blood,resolving stasis,softening hardness,and dissipating binds.Depending on the particular syndrome,variations on these major approaches to TCM therapy and related auxiliary nursing care are applied.
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