有氧运动对不同月龄SD雄性大鼠肌糖元、肝糖元含量的影响

摘要

目的：：探讨有氧运动对不同月龄SD雄性大鼠股四头肌肌糖元含量、Ca2+-ATPase、Na+-k+-AT-Pase活性及肝组织中肝糖元含量的影响。方法：取清洁级SD雄性大鼠60只,分为3月龄对照组、3月龄运动组、7月龄对照组、7月龄运动组、13月龄对照组和13月龄运动组。每组10只,运动组参照T. G. Bedford标准,采用跑台进行有氧运动。8周后麻醉分别取肝脏和肌组织进行实验分析。结果：1.经过8周有氧运动3月龄、7月龄、13月龄运动组与对照组相比肌糖元含量有高度显著性增加(P<0.01),3月龄运动组与对照组肝糖元含量有显著性增加(P<0.01),3月龄与7月龄对照组大鼠肌糖元含量无统计学差异,13月龄大鼠体内肌糖元含量下降并与其它两组具有统计学差异(P<0.05),三组对照组肝糖元含量无统计学差异。2. Ca2+-ATPase、Na+-k+-ATPase的活性运动组与对照组相比有高度显著性增加(P<0.01),对照组三种酶活性比较有显著性差异。结论：有氧运动可有效提高不同月龄SD雄性大鼠肌糖元的含量和ATPase的活性,随着年龄增长肝糖元含量和 ATPase 的活性下降。%The aim of the paper is to probe the influence of the aerobic exercise on the muscular glycogen contents of the SD Male bandicoot quadriceps,the liveness of Ca2+-ATPase、Na+ -K+ -ATPase,and the hepatic glycogen of the hepatic tissue. Method:to take 60 clean SD male bandicoots as the examples,which were divided into 3 -month control groups,3-month training group,7-month control groups,7-month training group,13-month con-trol groups and 13 - month training group. Each group contains 10 bandicoots. Referring to the T. G. Bedford standard,the training groups do the aerobic exercise by u-sing the treadmill. Eight weeks later, they will be anaes-thetized, eviscerated the liver and muscular tissues, and then analyzed. Result:through 8 weeks aerobic exercise the muscular glycogen of the 3-month,7-month and 13-month bandicoots increased significantly ( P <0 . 01 ) , compared with the control groups. The hepatic glycogen of both training groups and control groups of the 3 -month bandicoots increased significantly(P<0. 01),the muscu-lar glycogen in both 3 - month and 7 - month control groups do not show any statistical difference. The muscu-lar glycogen of 13 - month bandicoots decreased and shows the significant difference compared with other two groups(P<0. 05). While the hepatic glycogen doesn’t not show any statistical difference in three control groups. The liveness of Ca2+ -ATPase、Na+ -K+ -ATPase in train-ing groups shows the significant increase ( P<0 . 01 ) com-pared with the control group. The enzymatic activity in the control group shows the significant difference. Conclusion:the aerobic exercise can effectively increase the muscular glycogen contents and the liveness of the ATPase of the different month SD male bandicoots. The older they grow, the less they own the hepatic glycogen and the liveness of ATPase.