目的 研究亚临床甲状腺功能减退症(亚临床甲减)对血压的影响.方法 在进行甲状腺功能检查的1621例患者中,根据血清TSH、FT3、FT4结果,分别选取亚临床甲减患者120例(亚临床甲减组),甲状腺功能正常者120例(正常对照组)作为研究对象.测量2组的血压、身高和体质量,比较2组的收缩压(SBP)、舒张压(DBP)和平均动脉压( MAP)水平,分析亚临床甲减患者高血压患病的危险性.结果 排除年龄、性别、BMI等因素的影响,亚临床甲减组的SBP、DBP和MAP水平与正常对照组相比差异无统计学意义(P＞0.05)；亚临床甲减组高血压患病的危险性显著高于正常对照组(OR=2.15,95%CI 1.01～4.60,P=0.04).结论 亚临床甲减对SBP、DBP和MAP没有影响,但会增加患者高血压患病的危险性.%Objective To study the effect of subclinical hypothyroidism on blood pressure. Methods Among 1621 subjects who received thyroid function test, 120 subclinical hypothyroidism subjects (subclinical hypothyroidism group) and 120 euthyroidism subjects (normal control group)were selected according to the concentrations of serum TSH,FT3 and FT4. Blood pressure, height and body weight were measured in all subjects. Systolic blood pressure (SBP), diastolic blood pressure(DBP) and mean arterial pressure(MAP) were compared between the two groups. The risk of hypertension was analyzed in subclinical hypothyroidism group. Results After adjustment for age, sex and body mass index, no significant differences in SBP,DBP and MAP were found between subclinical hypothyroidism group and normal control group (P＞0. 05). But the risk of hypertension in subclinical hypothyroidism group was significantly higher than that in normal control group(OR= 2.15,95% CI 1.01-4. 60,P=0. 04). Conclusion Although subclinical hypothyroidism has no effect on SBP,DBP and MAP,it can increase the risk of hypertension.
展开▼
