Objective To investigate the relationship between serum low testosterone level and prostate cancer detection risk in a biopsy population.Methods A total of 107 men who underwent initial 12-core transrectal prostate biopsy at our institution were included in this retrospective study.The patients were divided into two groups:low testosterone level group (＜250 ng/dL) and normal testosterone level group (≥250 ng/dL).The mean age,body mass index (BMI),serum prostate-specific antigen (PSA) level,prostate volume,and Gleason score of all patients were analyzed.Results Among all 107 patients,19 (17.6 ％) had serum low testosterone level,and 88 (82.4 ％) had normal testosterone level.There were no statistical differences in the mean age,BMI,PSA level,and prostate volume between the two groups.Serum low testosterone level was significantly associated with a higher risk of prostate cancer than the normal testosterone level (P＜0.05).Conclusion Serum low testosterone level is an independent risk factor for high-grade prostate cancer detection in biopsy.%目的 分析血清低睾酮水平对前列腺穿刺活检结果的影响.方法 回顾性分析2011年3月至2016年11月在本院行前列腺穿刺检查确诊为前列腺癌的107例患者的临床资料.将患者分为低睾酮组(＜250 ng/dL)和正常睾酮组(≥250 ng/dL).采集患者的年龄、体质指数(BMI)、血清前列腺特异抗原(PSA)水平、前列腺体积和活检的Gleason评分.结果 本研究中19例(17.6％)患者为血清低睾酮水平,88(82.4％)例患者为正常睾酮水平.两组患者在年龄、BMI、血清PSA水平和前列腺体积方面无统计学差异(P＞0.05).血清低睾酮与高级别前列腺癌症检出率显著相关(P＜0.05).结论 血清低睾酮水平患者与高级别前列腺癌相关.
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