Objective:To explore the clinical difference of TPS-ZOOM function in the volume delineation of lung tumor SBRT target. Methods:The visible lesions of 25 lung cancer patients were analyzed clinically. 17 lesions were≤3 cm,3 cm ＜8 lesions≤5 cm. In the 10 groups of scaling images,GTVx＝(1,1.5,2,2.5,3,4,5,6,7,8)were mapped on 10 groups of 25 GTV for each group of 25 GTV,with a total value of 100%,150%,200%,250%,300%,400%,500%, 600%,700%,and 800% respectively. The use of SPSS 20. 0 in each focus was analyzed by spearman correlation,sin-gle factor ANOVA test showed the difference between the 10 groups,P＜0. 05 was statistically significant. Results:92%(23/25)lesions were negatively correlated with different scaling values. 10 groups data total comparison F value＝0. 178,P＝0. 916 was not statistically significant. The F values of the lesion ≤3 cm group and ＞3～5 cm group were 0. 176 and 0. 272 respectively . The P values were 0. 900 and 0. 980 respectively,and no significant difference was found . Conclusion :In the case of lung lesion less than 5 cm,GTV showed a general negative correlation with the scaling of TPS-ZOOM,but no significant statistical difference was observed in the overall scaling group. Howev-er,because of the small size of the lesion GTV in the treatment of SBRT in the lung,it is easier for clinicians to identi-fy the lesion edge of the lesion and suggest a scale of 150% to 200%.%目的:探索TPS(放射治疗计划系统)-ZOOM(缩放)功能在肺肿瘤立体定向体部放射治疗(ster-eotactic body radiation therapy,SBRT)靶区体积勾画中的临床差异.方法:临床分析25个肺内拟行SBRT治疗的可见病灶;其中17个病灶≤3 cm,3 cm＜8个病灶≤5 cm.同一个放疗医师分别在TPS-ZOOM取值为100%、150%、200%、250%、300%、400%、500%、600%、700%、800%等 10组缩放图像上分别勾画GTVx＝(1,1. 5,2,2. 5,3,4,5,6,7,8)每组25个GTV共计250个病灶数据信息.采用 SPSS 20. 0对每一个病灶均采用Spearman行相关性分析;ANOVA方差分析检验 10组间的勾画差异,P＜0. 05为统计学有差异.结果:92%(23/25)病灶体积与缩放值大小呈负相关;10组数据总体比较 F ＝0. 178,P＝0. 916,无统计学差异;分层分析≤3 cm组和 ＞3 ～5 cm组 F分别为0. 176和0. 272,P值分别为0. 900和0. 980,均未见统计学差异.结论:对小于5 cm的肺部病灶,各病灶缩放值与靶区体积呈一定负相关,但总体各缩放值体积数据间未见统计学差异;因拟行SBRT的病灶体积较小,为了便于临床医师较易识别病灶边缘与勾画靶区,建议缩放150% ～200%.
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