目的：探讨慢性阻塞性肺疾病（COPD）患者合并高血压和糖/脂代谢紊乱的发病状况及其影响因素。方法选取2001年4月至2011年7月就诊于石河子大学医学院第一附属医院住院的1376例COPD患者，回顾性分析COPD合并高血压和糖/脂代谢紊乱的发病状况，同时对导致COPD合并高血压和糖/脂代谢紊乱发生的影响因素进行分析。结果（1）COPD患者中合并高血压、糖尿病/糖耐量异常、高脂血症/脂蛋白代谢紊乱的发病率分别为41.1%、17.2%、9.2%。（2）就合并高血压、糖尿病/糖耐量发病率而言，3个不同年龄段比较，差异均有统计学意义（P<0.01）；60~<80岁患者高脂血症／脂蛋白代谢紊乱发病率较40~<60岁患者更高，差异有统计学意义（P<0.05）。（3）男性患者中COPD合并高血压、糖尿病/糖耐量异常、高脂血症/脂蛋白代谢紊乱的发病率为36.0%、16.5%、4.8%，女性患者中该比率分别为47.6%、22.3%、10.8%，两组比较，差异均有统计学意义（P<0.01）。（4）50~<60岁、60~<70岁女性患者的高血压患病率较男性高，差异均有统计学意义（P<0.05），其中以60~<70岁阶段差异最为显著。随着年龄的增大，女性患者高脂血症/脂蛋白代谢紊乱发病率较男性高，在70~<80岁阶段最为明显，差异有统计学意义（P<0.05）。结论年龄和性别均能影响COPD合并高血压和糖/脂代谢紊乱的发生，为临床上预防和治疗COPD合并症提供理论指导。%Objective To approach the morbidity and the influencing factors of hypertension and glucose/lipid metabolism induced by chronic obstructive pulmonary disease(COPD). Methods A retrospective prevalence survey on 1 376 COPD inpatients with hypertension and glucose and lipid metabolism disorders from April 2001 to July 2011 in the First Affiliated Hospital ,Medi-cal Hospital of Shihezi University was conducted,whose influencing factors were analyzed correlatively. Results (1)The incidence rates of COPD patients with hypertension,glucose/lipid metabolism,hyperlipemia/lipoprotein metabolism disorders were respec-tively 41.1%,17.2%,9.2%. (2)Referring to the hypertension,incidence of diabetes and glucose tolerance,there was statistical significance between the difference age sections(P<0.01);the incidence of hyperlipemia/lipoprotein metabolism disorders in the patients aged 60-<80 years old was higher than that of ones aged 40-<60 years old. It was statistically significant in difference (P<0.05);(3)The incidence rates of the male COPD patients with hypertension,glucose/lipid metabolism,hyperlipemia/lipopro-tein metabolism disorders were 36.0%,16.5%,4.8%respectively. The incidence rates of the female COPD patients with hyperten-sion,glucose/lipid metabolism,hyperlipemia/lipoprotein metabolism disorders were 47.6%,22.3%,10.8% respectively. The two groups had statistical significance in difference (P<0.01). (4)The prevalence of the female patients with hypertension aged 50-<60,60-<70 years old was higher than that of the male patients,whose difference was statistical significant(P<0.05). hose differ-ence aged 60-<70 years old was most remarkable. The difference was statistically significant (P<0.05). With increasing of the age, the female patients were higher than that of the male ones in prevalence of hyperlipidemia/lipoprotein metabolism ,especially aged 70-<80,whose difference had statistical significant(P<0.05). Conclusion Both age and gender can affect the incidence of COPD patients with high blood pressure and glucose/lipid metabolism disorder,and that provide theoretical guidance for the clinical compli-cations prevention and treatment of COPD.
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