Objective To understand the epidemiological characteristics of hand foot and mouth disease (HFMD) in Wuzhong District of Suzhou City from 2011 to 2015 in order to provide the scientific basis for formulating the targeted prevention and control strategy. Methods The descriptive epidemiological research method was adopted to analyze the cases information collected from the National Disease Reporting Information System. Results A total of 10 915 cases of HFMD were reported in Wuzhong District within these 5 years,the mean annual incidence rate was 191.63/100 000. In addition to significant increase of incidence rate during 2014,the rest annual incidence rate changed little. The onset was concentrated at the infants and young children aged 5 years old or below,accounting for 94.0%(10 260/10 915),moreover the incidence rate in males was higher than that in females. The incidence rate in urban areas was higher than that in suburban areas. The onset time had obvious seasonal characteristics,the reported cases were fewer from February to March and the onset peak was summer and autumn. Conclusion The incidence rate of HFMD is higher in Wuzhong District. So the control of epidemic situation in the infants and young children aged 5 years old or below should be strengthened ,the health education of the floating population should be paid more attention , moreover the two seasons of summer and autumn are the seasons as the focus of prevention and control.%目的：了解2011~2015年苏州市吴中区手足口病流行病学特征，为制定针对性的防控策略提供科学依据。方法采用描述性流行病学研究方法，对从中国疾病预防控制信息系统收集的吴中区病例信息进行分析。结果5年内吴中区共报告手足口病10915例，平均年发病率为191.63/10万。除2014年发病率显著增高外，其余年发病率变化不大。发病主要集中在5岁及以下婴幼儿，占94.0%（10260/10915），且男性发病率高于女性；城镇发病率高于城郊；发病时间具有明显的季节性特征，每年2~3月病例报告较少，夏、秋季为发病高峰。结论吴中区手足口病发病率较高，要加强5岁及以下婴幼儿疫情防控，重视流动人口的健康教育，并以夏、秋两季为重点防控季节。
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