速度向量成像技术评价颈动脉软斑块稳定性研究

摘要

Objective To preliminarily explore the application value of veloctiy vector imaging (VVI)technique in evalu-ating the stability of the carotid arterial soft plaques in the patients with essential hypertension complicating diabetes. Methods Totally 60 research subjects were selected and divided into the essential hypertension (EH) group(20 cases),EP complicating type 2 diabetes mellitus(T2DM) group(20 cases) and control group(20 cases). The VVI software was used to calculate the technology to detect the strain peak value and strain rate of the plaque shoulder ,top and intima corresponding point of same section and compared with the arterial wall motion parameters in the normal control group. Results The monolayer short axis section with maximal thickness:the strain peak value at intimal 1-6 points in the control group show no statistically significant differences (P>0.05);which had statistically significant difference between the EH group and the EP complicating T2DM group (P<0.05),i.e., the intimal strain peak values in the shoulder and top of plaque were significantly higher than the detected intimal values in the corresponding point of the same section(P<0.05). The intimal strain peak values in the shoulder and top of plaque was statistically significant between the EH group and EH complicating T2DM group (P<0.05). Conclusion The VVI technique can be used to e-valuate the stability of carotid soft plaque by detecting the strain and strain rate and provides a new method for detecting vulnera-ble plaque.%目的初步探讨速度向量成像技术（VVI技术）分析评价原发性高血压合并2型糖尿病患者颈动脉软斑块稳定性的临床应用价值。方法选取研究对象60例，分为原发性高血压组（n=20）、高血压合并2型糖尿病组（n=20），对照组（n=20）；运用VVI软件计算斑块肩部、顶部及同一切面内膜对应点应变峰值及应变率，并与正常对照组动脉壁运动参数进行比较。结果最大厚度单层短轴切面：对照组患者血管内膜1-6点应变峰值比较，差异无统计学意义（P>0.05），原发性高血压组和高血压合并2型糖尿病组患者斑块段血管内膜1-6点应变峰值比较，差异有统计学意义（P<0.05），即斑块处肩峰、顶部内膜应变峰值显著高于同一切面对应点内膜测值（P<0.05）。高血压合并2型糖尿病组与高血压组斑块处肩峰、顶部血管内膜应变峰值比较，差异有统计学意义（P<0.05）。结论 VVI技术可以检测颈动脉软斑块的应变及应变率来评估斑块的稳定性，为易损斑块的检测提供了新的方法。