目的：测定老年慢性心衰患者的血浆N-末端脑钠素前体（NT-pro BNP）和心率震荡（HRT）水平，探讨血浆NT-Pro BNP和HRT值对心衰的临床价值的评估。方法：选择本院住院心力衰竭（CHF）的住院患者80例组成，其中男、女比例不限；对照组80例，为心功能正常者。两组年龄、性别差异无显著意义（ P＞0．05），具有可比性。心衰患者测定NT-pro BNP＞5000pg/ml和TS≤3．0的患者。分为好转组和死亡组。随访1年。两组比较分析。结果：老年CHF患者与老年健康者NT-pro BNP、窦性 HRT 存在明显差别（P＜0．05）；老年CHF组NT-pro BNP（4967．04±366．16）pg/ml明显高于对照组（416．21±146．54）pg/ml（P＜0．001）；老年CHF组TO（0．76±3．42）明显高于对照组（-1．61±2．05）（P＜0．05）；老年CHF组TS（2．53±1．21）明显低于对照组（9．56±4．03）（P＜0．05）。老年CHF组LVEF（38．37±12．15）％明显低于对照组的（66．52±13．05）％（P＜0．05）。结论：慢性心衰患者的 NT-pro BNP＞5000pg/ml和TS≤3．0死亡率高。%Determination of plasma N-terminal pro brain natriuretic peptide in elderly patients with chronic heart failure (NT-pro BNP) body and heart rate turbulence (HRT ) level ,evaluation of plasma NT-pro BNP and HRT clinical value of the heart failure .Methods :The hospitalized heart failure (CHF) of 80 cases of patients ,male ,female ra-tio is not restricted ;control group :80 patients ,for patients with normal cardiac function .No significant gender differ-ences in two age groups ,(P> 0 .05) ,with comparable .Determination of NT-pro BNP ,5 000pg/ml in patients with heart failure and TS ≤ 3 patients .Divided into improved group and death group .1 year of follow-up .Comparative a-nalysis of two groups .Results:In elderly CHF patients and healthy elderly subjects NT-pro BNP ,sinus HRT significant differences (P<0 .05);elderly group CHF NT-pro BNP(4 967 .04 ± 366 .16)pg/ml was significantly higher than the control group (416 .21 ± 146 .54)pg/ml(P< 0 .001);aged CHF group TO(0 .76 ± 3 .42) was significantly higher than that of control group (-1 .61 ± 2 .05) (P<0 .05);aged CHF group TS (2 .53 ± 1 .21) was significantly lower than that of the control group (9 .56 ± 4 .03) (P<0 .05) .The aged CHF group LVEF (38 .37 ± 12 .15)% was significantly lower than that of the control group (66 .52 ± 13 .05)% (P<0 .05) .Conclusion :In patients with chronic heart failure NT-pro BNP ,5 000pg/ml and TS≤ 3 high mortality .
展开▼
