炎症标记物（C 反应蛋白和降钙素原）与颅内感染患者预后的关系

摘要

Objective :To study and investigate the relationship between the inflammatory markers (C‐reactive protein and procalcitonin) and prognosis of patients with intracranial infection .Methods :54 patients with intracranial infection in our hospital from March 2012 to March 2014 were selected as observation group ,54 healthy persons with health ex‐amination at the same time were the control group ,then the serum C‐reactive protein and procalcitonin levels and posi‐tive rates of two groups were respectively analyzed and compared ,then compared to the serum C‐reactive protein and procalcitonin levels and positive rates of observation group with different infection degree and treatment effect were re‐spectively .Results:The serum C‐reactive protein and procalcitonin levels and positive rates of observation group were all respectively higher than those of control group ,and the serum C‐reactive protein and procalcitonin levels and positive rates of observation group with severe infection and worse treatment effect were respectively higher than those of pa‐tients with mild infection and better treatment effect ,all P<0 .05 ,there were all significant differences .Conclusion:The serum C‐reactive protein and procalcitonin have higher clinical detection value for the intracranial infection ,and it can effectively react the prognosis of patients with intracranial infection .%目的：探讨炎症标记物（C反应蛋白和降钙素原）与颅内感染患者预后的关系。方法：选取2012年3月－2014年3月于本院进行诊治的54例颅脑感染患者为观察组，同期54名体检健康者为对照组，然后将两组的血清C反应蛋白和降钙素原水平及阳性率分别进行统计及比较，同时比较观察组中不同感染程度及治疗效果患者的血清C反应蛋白和降钙素原水平及阳性率。结果：观察组的血清C反应蛋白和降钙素原水平及阳性率均高于对照组，观察组中感染较重及治疗效果较差患者的检测水平和阳性率分别高于感染较轻及治疗效果较好的患者，均有显著性差异（P均＜0．05）。结论：血清C反应蛋白和降钙素原对颅内感染有较高的临床检测价值，可有效反应此类患者的预后。