Objective To investigate the prevalence of denture stomatitis in elderly patients over 50 years old wearing upper denture. To identify the most common Candida species and to analyze the affect factors. Methods 84 elderly patients wearing upper denture were examined. Their saliva and plaque from the palatal fitting surface of denture were cultured. The germ tube test and CHROMagar Candida were used to identify Candida species. Combined with clinical manifestations, denture stomatitis was diagnosed. Logistic regression was used to explain factors predisposing to Candida infection. Results Among the 84 individuals wearing upper denture,27 patients had denture stomatitis,which constituted 32. 1% of examined people. 100% patient had positive fungal cultures,of which 6 with Candida carrige and other 21 with Candida infection. No patients with denture stomatitis had negative culture. Calculated statistically, wearing dentures over night was a predisposing factor to denture stomatitis(P = 0. 007) ; women might be more predisposing to denture stomatitis than men( P =0. 055 ) . C. Albicans was significantly associated with denture stomatitis( P = 0.005 ) . Conclusion C. Albicans constituted most percentage of Candida species. It was common in the oral cavity with the most potent pathogenicity and significantly associated with denture stomatitis ( P = 0. 005 ). Wearing dentures over night was a predisposing factor to denture stomatitis( P = 0. 007 ) .%目的 调查口腔修复科门诊戴用可摘义齿50岁以上中老年患者义齿性口炎检出情况以及患者念珠菌培养情况,分析与义齿性口炎相关的因素.方法 检查戴用上颌跨过中线的可摘义齿中老年患者84人,用全唾液培养和义齿腭部组织面菌斑培养以及血清芽管实验和科玛嘉(CHROMagar)念珠菌显色培养基检查口腔念珠菌携带情况并初步鉴定菌种,结合临床表现诊断义齿性口炎.Logistic多因素回归分析可能与义齿性口炎患病相关的因素.结果 戴用可摘义齿的84位受检者中检出义齿性口炎患者27人,占32.1％.全部培养出念珠菌,其中口炎伴真菌携带者6人,占义齿性口炎患者的22.2％；口炎伴真菌感染者21人,占义齿性口炎患者的77.8％；未发现口炎不伴有真菌携带者.经统计分析,夜间戴用为义齿性口炎患病的影响因素(P＝0.007)；女性可能更易患义齿性口炎(P＝0.055).白念珠菌和义齿性口炎的患病高度相关(P＝0.005).结论 白念珠菌仍是口腔中致病性最强的念珠菌与义齿性口炎高度相关(P＝0.005).夜间戴用义齿和义齿性口炎高度相关(P＝0.007).
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