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垂体转移癌的诊治

     

摘要

目的 垂体转移癌为罕见鞍区恶性肿瘤.文中探讨垂体转移癌的临床表现与MRI特点,总结垂体转移癌的治疗经验. 方法 回顾性分析1例经手术病理确诊为垂体转移癌患者的临床资料、治疗方法. 结果 转移灶位于垂体柄和垂体后叶,呈浸润性生长,T1WI呈等低信号,T2WI呈等高混杂信号,哑铃状,中等强化;临床表现有尿崩症、垂体前叶功能减退、视力下降,误诊为垂体腺瘤;接受开颅手术治疗,肿瘤次全切除,术后放化疗. 结论 手术可明确垂体转移癌病理诊断及缓解患者临床症状,术后需综合治疗,同时积极寻找原发灶.%Objective Pituitary metastatic cancer is a rare malignant tumor in the sella region. This study was to investigate the clinical features, MRI characteristics and treatment of pituitary metastases. Methods We retrospectively analyzed the clinical data of 1 case of pituitary metastasis diagnosed by pathological examination. Results The metastatic tumor was located in the pituitary stalk and posterior lobe, with infiltration of the adjacent tissue and equal or slightly low signals on Tl WI and equal or slightly high signals on T2WT. Its clinical presentations included diabetes insipidus, hypofunction of the anterior lobe of the pituitary gland, and visual deterioration. Craniotomy was performed for subtotal removal of the tumor, followed by chemotherapy. Conclusion Surgery is necessitated for the pathological diagnosis of pituitary metastatic cancer and relief of the symptoms, and comprehensive therapy is necessary postoperatively.

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