多支架辅助弹簧圈治疗颈内动脉血泡样动脉瘤的疗效分析

摘要

Objective The treatment methods for blood blister-like aneurysm remain controversial due to its special patholog-ical structure,the risk of post-operative rebleeding and the high rate of recurrence. The arm of this paper is to access the feasibility and effectiveness of overlapping stent-assisted coiling in the treatment of blood blister-like aneurysms of the internal carotid artery. Methods Form January 2014 to December 2016,we treated 15 patients with blood blister-like aneurysm of the internal carotid artery by stent-assisted coiling in the Department of Neurosurgery,5 with two Enterprise tents,3 with three Enterprise tents,4 with Enter-prise+LVIS tents,and 3 with two LVIS tents. We determined the rate of immediate embolization of aneurysms by Raymond-Roy Occlu-sion Classification(RROC)and analyzed the clinical characteristics,postoperative complications,and follow-up data. Results All the coils and stents were successfully implanted. RROC showed 9 cases of gradeⅠ(60%),4 cases of gradeⅡ(27%),and 2 cases of gradeⅢimmediate occlusion(13%),with the parent arteries unobstructed in all the cases. Thrombosis in the stent was found in 2 cases intraoperatively,slight stent migration in 1 case,and internal carotid artery dissection in the petrous segment in another,but no cer-ebral vasospasm or aneurysm rupture in any case.Delayed cerebral in-farct was observed in 2 cases postoperatively. The patients were fol-lowed up for 2 weeks to 28 months,which showed that 11 of them were cured,2 remained stable and 2 developed further thrombosis,with an MRS score of 0-2 in 12 cases,4 in 1 case,5 in 1 case, and 6 in 1case. Conclusion Overlapping stent-assisted coiling is effective for the treatment of blood blister-like aneurysm by reduc-ing the risks of rebleeding and recurrence.%目的 由于血泡样动脉瘤特殊的病理结构,显微手术治疗的再出血及复发率较高,治疗方式仍存在争议.文中探讨多支架辅助弹簧圈治疗颈内动脉血泡样动脉瘤的可行性和有效性. 方法 回顾性分析皖南医学院附属弋矶山医院2014年1月至2016年12月经多支架结合弹簧圈栓塞颈内动脉血泡样动脉瘤15例,其中双Enterprise 5例、三重Enterprise 3例、Enterprise+Lvis 4例、双Lvis支架3例.所有病例均采用支架辅助弹簧圈栓塞术.分析纳入病例临床特点、即刻栓塞率(采用Raymond分级)、临床随访结果、并发症及影像学随访情况. 结果 采用多支架辅助弹簧圈栓塞方法成功治疗15例,弹簧圈和支架植入成功率100%.动脉瘤即刻Raymond分级显示:RaymondⅠ级9例、RaymondⅡ级4例、RaymondⅢ级2例.所有患者载瘤动脉均保持通畅.术中仅2例出现支架内血栓,1例出现支架少许移位,1例出现颈内动脉岩骨段夹层,无动脉瘤术中破裂、飞圈等术中并发症,术后有迟发型脑梗死2例.术后影像学随访2周~25个月,其中治愈11例、稳定2例、进一步血栓形成2例;临床随访2周~28个月,改良Rankin评分为0~2分者12例、4分1例、5分1例、6分1例. 结论 多支架结合弹簧圈栓塞颈内动脉血泡样动脉瘤具有一定有效性,可降低BBAs的再出血及复发的风险.