胰腺神经内分泌肿瘤的MDCT诊断

摘要

Objective To investigate the value of the MDCT(Multi-detector Computed Tomography)in the diagnosis of the pancreatic neuroendocrine neoplasms.Methods We reviewed 21 cases of pancreatic neuroendocrine neoplasms confirmed by pa-thology in our hospital from November 2010 to June 2016.All the patients underwent MDCT examination.Results Of all the 21 cases,13 cases were functional tumors and 8 cases were unfunctional.Among them,17 cases were PNET(pancreatic neuroendo-crine tumour)and 3 were PNEC(pancreatic neuroendocrine carcinoma),1 was MANEC(mixed adenoendocrine carcinoma),12 cases were solid and 9 were cystic-solid.16 cases were obvious enhancement,3 and 2 were moderate and mild enhancement,re-spectively.Most of the PNET cases were manifested as obvious enhancement,but the PNEC ones mainly showed moderate or mild enhancement.There was statistically significant difference between them(P <0.05).The density of PNET cases tended to be more homogeneous than the PNEC,without statistically significant difference(P >0.05).Conclusion MDCT has great value in the diagnosis of the pancreatic neuroendocrine neoplasms,and could effectively help the clinical treatment.%目的 探讨MDCT(Multi-detector Computed Tomography)在胰腺神经内分泌肿瘤(pancreatic neuroendocrine ne-oplasm,pNENs)诊断及鉴别诊断中的应用价值.方法 回顾2010年11月~2016年6月21例在我院经病理确诊的胰腺神经内分泌肿瘤病例资料,均行MDCT检查.结果 21例病例中,功能性肿瘤13例,非功能性8例;其中神经内分泌瘤17例,神经内分泌癌3例,混合性腺神经内分泌癌1例.CT平扫12例为实性,9例为囊实性;三期增强扫描示16例呈明显强化,3例中度强化,2例轻度强化;神经内分泌瘤主要表现为明显强化,内分泌癌以轻中度强化为主,差异有统计学意义(P <0.05);神经内分泌瘤的强化方式多较均匀,内分泌癌强化欠均匀,两者比较差异无统计学意义(P >0.05).结论 MDCT对胰腺神经内分泌肿瘤诊断有很大的应用价值,能够有效的帮助临床进行治疗.