缓解期风火候偏头痛患者脑白质DTI的TBSS分析

摘要

Objective To study the DTI characteristics of migraine patients with feng huo syndrome , and to explore the chan-ges of white matter fibers in migraine patients .Methods Twenty three migraine patients and twenty five healthy volunteers un-derwent DTI scanning .The DTI data were analyzed by PANDA treatment software based on tract-based spatial statistics ( TBSS) analysis .Results Compared with the control group , there were five brain areas of migraine patients with feng huo syndrome with FA values decreased ( P <0.05), which were corpus callosum , right cingulate gyrus, right occipital lobe, right temporal lobe, right cerebellum .Conclusion Compared with the control group , the FA value of multiple brain regions decreased , suggesting that the microstructure of the related brain area of migraine patients with feng huo syndrome had changed .%目的 探讨缓解期风火候偏头痛患者脑DTI特点及其脑白质结构的改变.方法 收集23例偏头痛风火候患者与25名健康志愿者的DTI图像,通过PANDA处理软件,进行基于纤维束追踪空间统计分析(tract-based spatial statis-tics,TBSS)分析,观察患者组与健康志愿者在大脑功能及结构上的差异.结果 相对于对照组,风火候偏头痛组患者5个脑区的FA值在显著降低(P<0.05),分别为胼胝体、右侧扣带回、右侧枕叶、右侧颞叶、右侧小脑.结论 相对于对照组,风火候偏头痛组部分脑区的白质结构已经发生改变.