Objective To discuss the clinical value of multi-slice spiral computed tomography (MSCT) combining techneti-um-99mmethoxyisobutylisonitrile (99m Tc-MIBI) lung carcinoma imaging in the diagnosis of solitary pulmonary nodule (SPN). Methods MSCT and 99mTc-MIBI lung carcinoma imagings were all taken in 96 patients who had the undetermined pulmonary nodule in chest X-ray. Then,we calculated the sensitivity,specificity and accuracy of two examinations and combination of them separately after compared with pathologic results and compared and analysed the data of them with statistical methods. Results The sensitivity,specificity and accuracy of two examinations of MSCT and 99mTc-MIBI lung carcinoma imaging had no significant difference,whereas,the sensitivity,specificity and accuracy of combination of them were higher than one of them,which had sig-nificant statistical difference. Conclusion The combination of MSCT and 99mTc-MIBI lung carcinoma imaging can greatly improve the sensitivity,specificity and accuracy of the diagnosis of SPN,which has a significant clinical value in the diagnosis of benign and malignant SPN.%目的 探讨多层螺旋 CT 联合99m锝-甲氧异丁基异腈(99m Tc-MIBI)亲肿瘤显像对孤立性肺结节的诊断价值.方法 对96例常规X线发现肺部性质不明确结节病灶患者均行多层螺旋CT和99mTc-MIBI亲肿瘤显像,再与最终的病理确诊结果作对比,分别计算出以上2种方法独立应用以及联合应用在诊断肺部结节病灶中的灵敏度、特异性、准确性,通过统计学方法将联合应用后的结果分别与单一方法进行比较分析.结果 多层螺旋CT和99mTc-MIBI亲肿瘤显像的灵敏度、特异性、准确性无明显差异;多层螺旋 CT 联合99mTc-MIBI亲肿瘤显像的灵敏度、特异性及准确性比单独多层螺旋 CT或单独99mTc-MIBI亲肿瘤显像要高,差异具有统计学意义.结论 多层螺旋 CT 联合99mTc-MIBI亲肿瘤显像大大提高了孤立性肺结节诊断的灵敏度、特异性和准确性,其联合应用对诊断孤立性肺结节良恶性具有重要的临床价值.
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