目的:探讨超声软指标在中孕期胎儿21-三体综合征诊断中的临床价值.方法:对2013年2月～2015年3月来某院进行产前筛查的2127例孕妇进行超声检查,分析超声软指标、胎儿结构畸形或其他异常情况与21-三体综合征的关系.结果:共筛查出超声1项软指标异常率12.4％,2项软指标异常者2.1％,3项软指标异常率0.3％,比较3项软指标异常率,P＜0.05.结论:在中孕期胎儿的结构发育检查中,21-三体综合征胎儿通常会出现软指标与结构畸形或其他异常情况,以及多个超声软指标共同出现的临床征象,可作为临床诊断的依据.%Objective:To explore the clinical value of ultrasound soft index in the diagnosis of 21-trisomy syndrome during middle pregnancy.Methods:2127pregnant women who underwent antenatal screening in a hospital from February 2013 to March 2015 were examined by ultrasound,and the relationship between ultrasound soft index,fetal structural malformation or other abnormalities and trisomy 21syndrome was analyzed. Results:The abnormal rate of 1,2 and 3soft index of ultrasound was 12.4％,2.1％ and 0.3％ respectively, compared the abnormal rates of 3soft indexes,P＜0.05.Conclusion:In the examination of fetal structure development during the middle pregnancy,21-trisomy syndrome fetuses usually appear soft index and structural deformity or other abnormal situation,as well as a number of clinical signs of multiple soft ultrasound indicators,which can be used as the basis of clinical diagnosis.
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