孤立性肺结节鉴别诊断中CT灌注成像结合动态增强扫描的临床价值

摘要

Objective:To study the clinical value of CT perfusion imaging combined dynamic enhanced scan in differential diagnosis of solitary pulmonary nodule.Methods:1 10 cases of patients with solitary pul-monary nodules were selected and treated with routine CT perfusion imaging combined dynamic enhanced scan,and then compared the pathological results.Results:The time-density curve of tuberculoma,inflam-matory nodules and small lung cancer patients had significant differences;BF,BV and PS parameter values of tuberculoma patients were significantly lower than that of patients with inflammatory nodules and small lung cancer (all P <0.01);PS parameter values of patients with inflammatory nodules was significantly low-er than that of small lung cancer patients,which the difference was statistically significant (P <0.01).Con-clusion:Treated with CT perfusion imaging combined dynamic enhanced scan,and taking advantage of time-density curve of tuberculoma,inflammatory nodules and small lung cancer patients and CT perfusion param-eters difference can improve the clinical differential diagnosis accuracy of SNP patients.%目的：：探讨孤立性肺结节鉴别诊断应用 CT 灌注成像结合动态增强扫描的临床价值。方法：选取某院110例孤立性肺结节患者，采用常规 CT 灌注成像结合动态增强扫描，并与病理检测结果进行对比分析。结果：结核瘤、炎性结节及小肺癌患者的时间-密度曲线存在显著差异；结核瘤患者的 BF、BV 及 PS 参数值明显低于炎性结节患者和小肺癌患者(均 P <0.01)；炎性结节患者的PS 参数值显著低于小肺癌患者，组间比较差异具有统计学意义(P <0.01)。结论：CT 灌注成像结合动态增强扫描，利用结核瘤、炎性结节及小肺癌换的时间-密度曲线以及 CT 灌注参数差异，能够提高对 SNP 患者的临床鉴别诊断准确率。